4XU3
Mycobacterium tuberculosis biotin ligase complexed with bisubstrate inhibitor 90 that has an acyclic ether in place of the ribose
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Bifunctional ligase/repressor BirA | polymer | 270 | 28534.4 | 2 | UniProt (A0A045H8W3) Pfam (PF03099) Pfam (PF02237) UniProt (by SIFTS) (I6YFP0) | Mycobacterium tuberculosis | Biotin--acetyl-CoA-carboxylase ligase,Biotin-protein ligase,BirA protein |
| 2 | C, E (A, B) | N-({2-[(6-amino-9H-purin-9-yl)methoxy]ethyl}sulfamoyl)-5-[(3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanamide | non-polymer | 513.6 | 2 | Chemie (44R) | |||
| 3 | D (A) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 4 | F, G (A, B) | water | water | 18.0 | 179 | Chemie (HOH) |
Sequence modifications
A, B: 2 - 266 (UniProt: A0A045H8W3)
| PDB | External Database | Details |
|---|---|---|
| Gly -3 | - | expression tag |
| Ser -2 | - | expression tag |
| His -1 | - | expression tag |
| Met 0 | - | expression tag |
| Val 1 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 57068.9 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 1062.6 | |
| All* | Total formula weight | 58131.5 |
