4XTY
Mycobacterium tuberculosis biotin ligase complexed with bisubstrate inhibitor 63 with Fluorine in place of 2'OH
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Bifunctional ligase/repressor BirA | polymer | 270 | 28534.4 | 2 | UniProt (A0A045H8W3) Pfam (PF03099) Pfam (PF02237) UniProt (by SIFTS) (I6YFP0) In PDB | Mycobacterium tuberculosis | Biotin--acetyl-CoA-carboxylase ligase,Biotin-protein ligase,BirA protein |
2 | A, B | 2',5'-dideoxy-2'-fluoro-5'-[({5-[(3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanoyl}sulfamoyl)amino]adenosine | non-polymer | 573.6 | 2 | Chemie (44L) | |||
3 | water | water | 18.0 | 332 | Chemie (HOH) |
Sequence modifications
A, B: 2 - 266 (UniProt: A0A045H8W3)
PDB | External Database | Details |
---|---|---|
Gly -3 | - | expression tag |
Ser -2 | - | expression tag |
His -1 | - | expression tag |
Met 0 | - | expression tag |
Val 1 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 57068.9 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 1147.2 | |
All* | Total formula weight | 58216.1 |