4XTD

Structure of the covalent intermediate E-XMP* of the IMP dehydrogenase of Ashbya gossypii

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Inosine-5'-monophosphate dehydrogenase,Inosine-5'-monophosphate dehydrogenase	polymer	413	44528.6	2	UniProt (Q756Z6) Pfam (PF00478)	Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056) (Yeast)	IMPDH,IMPDH
2	C, D (A, B)	INOSINIC ACID	non-polymer		348.2	2	Chemie (IMP)
3	E, F (A, B)	water	water		18.0	134	Chemie (HOH)

Sequence modifications

A, B: 1 - 231 (UniProt: Q756Z6)

PDB	External Database	Details
Gly -2	-	expression tag
Ser -1	-	expression tag
His 0	-	expression tag

A, B: 236 - 522 (UniProt: Q756Z6)

PDB	External Database	Details
Ser 232	-	linker
Gln 233	-	linker
Asp 234	-	linker
Gly 235	-	linker

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	89057.1
Non-Polymers*	Number of molecules	2
	Total formula weight	696.4
All*	Total formula weight	89753.5

*Water molecules are not included.