4XTA

MECHANISMS OF PPARgamma ACTIVATION BY NON-STEROIDAL ANTI-INFLAMMATORY DRUGS

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Peroxisome proliferator-activated receptor gamma	polymer	278	31734.9	2	UniProt (P37231) Pfam (PF00104)	Homo sapiens (Human)	PPAR-gamma,Nuclear receptor subfamily 1 group C member 3
2	C, D (A, B)	2-[2,6-DICHLOROPHENYL)AMINO]BENZENEACETIC ACID	non-polymer		296.1	2	Chemie (DIF)
3	E, F (A, B)	water	water		18.0	39	Chemie (HOH)

Sequence modifications

A, B: 204 - 477 (UniProt: P37231)

PDB	External Database	Details
Gly 200	-	expression tag
Ser 201	-	expression tag
His 202	-	expression tag
Met 203	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	63469.7
Non-Polymers*	Number of molecules	2
	Total formula weight	592.3
All*	Total formula weight	64062.0

*Water molecules are not included.