4XSC
Complex structure of thymidylate synthase from varicella zoster virus with a phosphorylated BVDU
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C, D | Thymidylate synthase | polymer | 311 | 35768.8 | 4 | UniProt (Q4JQW2) Pfam (PF00303) In PDB | Varicella-zoster virus (strain Oka vaccine) (HHV-3) | TSase |
2 | A, B, C, D | (E)-5-(2-BROMOVINYL)-2'-DEOXYURIDINE-5'-MONOPHOSPHATE | non-polymer | 413.1 | 4 | Chemie (BVP) | |||
3 | A, B, C, D | PENTAETHYLENE GLYCOL | non-polymer | 238.3 | 4 | Chemie (1PE) | |||
4 | water | water | 18.0 | 34 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 8 - 295 (UniProt: Q4JQW2)
PDB | External Database | Details |
---|---|---|
Met -15 | - | initiating methionine |
His -14 | - | expression tag |
His -13 | - | expression tag |
His -12 | - | expression tag |
His -11 | - | expression tag |
His -10 | - | expression tag |
His -9 | - | expression tag |
Ser -8 | - | expression tag |
Ser -7 | - | expression tag |
Gly -6 | - | expression tag |
Val -5 | - | expression tag |
Asp -4 | - | expression tag |
Leu -3 | - | expression tag |
Gly -2 | - | expression tag |
Thr -1 | - | expression tag |
Glu 0 | - | expression tag |
Asn 1 | - | expression tag |
Leu 2 | - | expression tag |
Tyr 3 | - | expression tag |
Phe 4 | - | expression tag |
Gln 5 | - | expression tag |
Ser 6 | - | expression tag |
Met 7 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 143075.4 | |
Non-Polymers* | Number of molecules | 8 |
Total formula weight | 2605.6 | |
All* | Total formula weight | 145681.0 |