4XS2

Irak4-inhibitor co-structure

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	Interleukin-1 receptor-associated kinase 4	polymer	301	33956.2	4	UniProt (Q9NWZ3) Pfam (PF07714)	Homo sapiens (Human)	IRAK-4,Renal carcinoma antigen NY-REN-64
2	E, F, G, H (A, B, C, D)	(1R,2S,3R,5R)-3-({5-(1,3-benzothiazol-2-yl)-6-chloro-2-[(3-methoxypropyl)amino]pyrimidin-4-yl}amino)-5-(hydroxymethyl)cyclopentane-1,2-diol	non-polymer		480.0	4	Chemie (42P)
3	I, J, K, L (A, B, C, D)	water	water		18.0	33	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	135824.8
Non-Polymers*	Number of molecules	4
	Total formula weight	1919.9
All*	Total formula weight	137744.7

*Water molecules are not included.