4XRQ
Disulfide stabilized HIV-1 CA hexamer 4mut (S41A, Q67H, V165I, L172I) in complex with PF-3450074
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Capsid protein p24 | polymer | 231 | 25469.3 | 1 | UniProt (P12493) Pfam (PF00607) Pfam (PF19317) In PDB | Human immunodeficiency virus 1 (HIV-1) | Pr55Gag, CA |
| 2 | A | N-METHYL-NALPHA-[(2-METHYL-1H-INDOL-3-YL)ACETYL]-N-PHENYL-L-PHENYLALANINAMIDE | non-polymer | 425.5 | 1 | Chemie (1B0) | |||
| 3 | water | water | 18.0 | 93 | Chemie (HOH) |
Sequence modifications
A: 1 - 231 (UniProt: P12493)
| PDB | External Database | Details |
|---|---|---|
| Cys 14 | Ala 146 | engineered mutation |
| Ala 41 | Ser 173 | engineered mutation |
| Cys 45 | Glu 177 | engineered mutation |
| His 67 | Gln 199 | engineered mutation |
| Ile 165 | Val 297 | engineered mutation |
| Ile 172 | Leu 304 | engineered mutation |
| Ala 184 | Trp 316 | engineered mutation |
| Ala 185 | Met 317 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 25469.3 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 425.5 | |
| All* | Total formula weight | 25894.8 |
