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4XRJ

Crystal structure of ERK2 in complex with an inhibitor

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Mitogen-activated protein kinase 1polymer34640403.61UniProt (P63086)
Pfam (PF00069)
Rattus norvegicus (Norway Rat)MAPK 1,ERT1,Extracellular signal-regulated kinase 2,ERK-2,MAP kinase isoform p42,p42-MAPK,Mitogen-activated protein kinase 2,MAPK 2
2B
(A)
N~1~-[3-(benzyloxy)benzyl]-1H-tetrazole-1,5-diaminenon-polymer296.31Chemie (620)
3C
(A)
SULFATE IONnon-polymer96.11Chemie (SO4)
4D
(A)
waterwater18.0161Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight40403.6
Non-Polymers*Number of molecules2
Total formula weight392.4
All*Total formula weight40796.0
*Water molecules are not included.

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PDB entries from 2025-06-11

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