4XP2
Crystal structure of ERK2 in complex with an inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Mitogen-activated protein kinase 1 | polymer | 351 | 40925.1 | 1 | UniProt (P63086) Pfam (PF00069) | Rattus norvegicus (Rat) | MAPK 1,ERT1,Extracellular signal-regulated kinase 2,ERK-2,MAP kinase isoform p42,p42-MAPK,Mitogen-activated protein kinase 2,MAPK 2 |
| 2 | B (A) | 1-phenyl-1H-1,2,4-triazole-3,5-diamine | non-polymer | 175.2 | 1 | Chemie (TT4) | |||
| 3 | C, D (A) | DIMETHYL SULFOXIDE | non-polymer | 78.1 | 2 | Chemie (DMS) | |||
| 4 | E, F (A) | SULFATE ION | non-polymer | 96.1 | 2 | Chemie (SO4) | |||
| 5 | G (A) | water | water | 18.0 | 273 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 40925.1 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 523.6 | |
| All* | Total formula weight | 41448.7 |
