4XOG
CRYSTAL STRUCTURE OF THE NANB SIALIDASE FROM STREPTOCOCCUS PNEUMONIAE IN COMPLEX WITH Optactin and DANA
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Sialidase B | polymer | 660 | 73720.1 | 1 | UniProt (Q54727) Pfam (PF02973) Pfam (PF02012) Pfam (PF13088) | Streptococcus pneumoniae TIGR4 | NANB SIALIDASE, Neuraminidase B |
| 2 | B (A) | 2-DEOXY-2,3-DEHYDRO-N-ACETYL-NEURAMINIC ACID | non-polymer | 291.3 | 1 | Chemie (DAN) | |||
| 3 | C (A) | (1s,3R,4S)-1-[(cyclohexylamino)methyl]-3,4-dihydroxycyclopentanesulfonic acid | non-polymer | 293.4 | 1 | Chemie (OPX) | |||
| 4 | D, E, F (A) | DIMETHYL SULFOXIDE | non-polymer | 78.1 | 3 | Chemie (DMS) | |||
| 5 | G (A) | water | water | 18.0 | 531 | Chemie (HOH) |
Sequence modifications
A: 37 - 694 (UniProt: Q54727)
| PDB | External Database | Details |
|---|---|---|
| Gly 643 | Asp 643 | engineered mutation |
| Leu 695 | - | expression tag |
| Thr 696 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 73720.1 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 819.0 | |
| All* | Total formula weight | 74539.1 |
