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4XNE

Crystal structure of ERK2 in complex with an inhibitor

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1AMitogen-activated protein kinase 1polymer34640403.61UniProt (P63086)
Pfam (PF00069)
In PDB
Rattus norvegicus (Norway Rat)MAPK 1,ERT1,Extracellular signal-regulated kinase 2,ERK-2,MAP kinase isoform p42,p42-MAPK,Mitogen-activated protein kinase 2,MAPK 2
2A1-phenyl-1H-1,2,4-triazole-3,5-diaminenon-polymer175.21Chemie (TT4)
3ASULFATE IONnon-polymer96.11Chemie (SO4)
4waterwater18.0126Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight40403.6
Non-Polymers*Number of molecules2
Total formula weight271.3
All*Total formula weight40674.8
*Water molecules are not included.

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PDB entries from 2024-09-18

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