4XNC
Crystal structure at room temperature of cyclophilin D in complex with an inhibitor
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Peptidyl-prolyl cis-trans isomerase F, mitochondrial | polymer | 164 | 17652.1 | 1 | UniProt (P30405) Pfam (PF00160) In PDB | Homo sapiens (Human) | PPIase F,Cyclophilin D,CypD,Cyclophilin F,Mitochondrial cyclophilin,CyP-M,Rotamase F |
2 | A | ethyl N-[(4-aminobenzyl)carbamoyl]glycinate | non-polymer | 251.3 | 1 | Chemie (EA4) | |||
3 | water | water | 18.0 | 65 | Chemie (HOH) |
Sequence modifications
A: 44 - 207 (UniProt: P30405)
PDB | External Database | Details |
---|---|---|
Ile 175 | Lys 175 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 17652.1 | |
Non-Polymers* | Number of molecules | 1 |
Total formula weight | 251.3 | |
All* | Total formula weight | 17903.4 |