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4XN4

Crystal Structure of Met260Ala mutant of E. coli Aminopeptidase N in complex with L-Methionine

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Aminopeptidase Npolymer86698480.01UniProt (P04825)
Pfam (PF17900)
Pfam (PF01433)
Pfam (PF11940)
Pfam (PF17432)
Escherichia coli K-12Alpha-aminoacylpeptide hydrolase
2B
(A)
ZINC IONnon-polymer65.41Chemie (ZN)
3C, D, E, F
(A)
METHIONINEnon-polymer149.24Chemie (MET)
4G, H, I, J, K...
(A)
SODIUM IONnon-polymer23.08Chemie (NA)
5O, P, Q
(A)
GLYCEROLnon-polymer92.13Chemie (GOL)
6R, S, T
(A)
MALONATE IONnon-polymer102.03Chemie (MLI)
7U
(A)
waterwater18.01231Chemie (HOH)
Sequence modifications
A: 5 - 870 (UniProt: P04825)
PDBExternal DatabaseDetails
Ala 260Met 260engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight98480.0
Non-Polymers*Number of molecules19
Total formula weight1428.6
All*Total formula weight99908.6
*Water molecules are not included.

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PDB entries from 2025-06-11

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