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4XN2

Crystal Structure of Met260Ala mutant of E. coli Aminopeptidase N in complex with L-Leucine

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Aminopeptidase Npolymer86698480.01UniProt (P04825)
Pfam (PF17900)
Pfam (PF01433)
Pfam (PF11940)
Pfam (PF17432)
Escherichia coli K-12Alpha-aminoacylpeptide hydrolase
2B
(A)
ZINC IONnon-polymer65.41Chemie (ZN)
3C
(A)
LEUCINEnon-polymer131.21Chemie (LEU)
4D, E, F, G, H...
(A)
SODIUM IONnon-polymer23.011Chemie (NA)
5O, P, Q
(A)
GLYCEROLnon-polymer92.13Chemie (GOL)
6R, S
(A)
MALONATE IONnon-polymer102.02Chemie (MLI)
7T
(A)
waterwater18.0985Chemie (HOH)
Sequence modifications
A: 5 - 870 (UniProt: P04825)
PDBExternal DatabaseDetails
Ala 260Met 260engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight98480.0
Non-Polymers*Number of molecules18
Total formula weight929.8
All*Total formula weight99409.8
*Water molecules are not included.

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PDB entries from 2025-06-11

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