4XMI
Crystal structure of the K499G mutant of NanB sialidase from Streptococcus pneumoniae
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Sialidase B | polymer | 658 | 73447.7 | 1 | UniProt (Q54727) Pfam (PF02973) Pfam (PF02012) Pfam (PF13088) In PDB | Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4) | Neuraminidase B |
| 2 | A | DIMETHYL SULFOXIDE | non-polymer | 78.1 | 6 | Chemie (DMS) | |||
| 3 | A | PHOSPHATE ION | non-polymer | 95.0 | 1 | Chemie (PO4) | |||
| 4 | water | water | 18.0 | 734 | Chemie (HOH) |
Sequence modifications
A: 39 - 696 (UniProt: Q54727)
| PDB | External Database | Details |
|---|---|---|
| Gly 499 | Lys 499 | engineered mutation |
| Gly 643 | Asp 643 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 73447.7 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 563.8 | |
| All* | Total formula weight | 74011.5 |
