4XM7
Anthrax toxin lethal factor with ligand-induced binding pocket
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Lethal factor | polymer | 519 | 60436.0 | 1 | UniProt (P15917) Pfam (PF09156) Pfam (PF07737) In PDB | Bacillus anthracis | LF,Anthrax lethal toxin endopeptidase component |
2 | A | N~2~-[(4-fluoro-3-methoxyphenyl)sulfonyl]-N-hydroxy-N~2~-(2-methylpropyl)-D-valinamide | non-polymer | 376.4 | 1 | Chemie (41S) | |||
3 | A | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
4 | A | 1,2-ETHANEDIOL | non-polymer | 62.1 | 1 | Chemie (EDO) | |||
5 | water | water | 18.0 | 32 | Chemie (HOH) |
Sequence modifications
A: 265 - 776 (UniProt: P15917)
PDB | External Database | Details |
---|---|---|
Ser 262 | - | expression tag |
Asn 263 | - | expression tag |
Ala 264 | - | expression tag |
Ser 266 | Ala 299 | engineered mutation |
Leu 777 | - | expression tag |
Val 778 | - | expression tag |
Pro 779 | - | expression tag |
Arg 780 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 60436.0 | |
Non-Polymers* | Number of molecules | 3 |
Total formula weight | 503.9 | |
All* | Total formula weight | 60940.0 |