4XLI
Crystal structure of Abl2/Arg kinase in complex with dasatinib
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Non-specific protein-tyrosine kinase | polymer | 268 | 30769.3 | 2 | UniProt (F8VQH0) Pfam (PF07714) UniProt (by SIFTS) (Q4JIM5) In PDB | Mus musculus (Mouse) | |
| 2 | A, B | N-(2-CHLORO-6-METHYLPHENYL)-2-({6-[4-(2-HYDROXYETHYL)PIPERAZIN-1-YL]-2-METHYLPYRIMIDIN-4-YL}AMINO)-1,3-THIAZOLE-5-CARBOXAMIDE | non-polymer | 488.0 | 2 | Chemie (1N1) | |||
| 3 | A | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 4 | water | water | 18.0 | 32 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 61538.7 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 1041.4 | |
| All* | Total formula weight | 62580.1 |
