4XL8
Crystal Structure of Human Adenovirus 52 Short Fiber Knob in Complex with 2-O-Methyl-5-N-Acetylneuraminic Acid
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | Fiber-1 | polymer | 209 | 22420.9 | 3 | UniProt (A0MK70) | Human adenovirus 52 | Adenovirus 52 short fiber knob |
| 2 | D, I (A, C) | 2-O-methyl-5-N-acetyl-alpha-D-neuraminic acid | non-polymer | 323.3 | 2 | Chemie (MNA) PubChem (446069) PubChem (5067510) PubChem (6409690) PubChem (14160669) PubChem (14160670) PubChem (15108907) PubChem (15108909) PubChem (21635522) PubChem (29983255) PubChem (40489130) PubChem (44119525) PubChem (44343219) PubChem (45039746) PubChem (51777068) PubChem (51777072) PubChem (5702845) PubChem (124349183) PubChem (71299535) PubChem (71750169) PubChem (92132242) PubChem (95608246) PubChem (96327161) PubChem (96327164) PubChem (97049943) PubChem (124800623) PubChem (126968463) PubChem (129360358) PubChem (129374373) PubChem (133688711) PubChem (134067226) PubChem (174858731) | |||
| 3 | E (A) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) PubChem (753) | |||
| 4 | F (B) | TRIS(HYDROXYETHYL)AMINOMETHANE | non-polymer | 163.2 | 1 | Chemie (TAM) PubChem (448009) | |||
| 5 | G (B) | GLUTAMIC ACID | non-polymer | 147.1 | 1 | Chemie (GLU) PubChem (611) PubChem (23327) PubChem (33032) | |||
| 6 | H (B) | ALANINE | non-polymer | 89.1 | 1 | Chemie (ALA) | |||
| 7 | J (C) | (4S)-2-METHYL-2,4-PENTANEDIOL | non-polymer | 118.2 | 1 | Chemie (MPD) | |||
| 8 | K (C) | (4R)-2-METHYLPENTANE-2,4-DIOL | non-polymer | 118.2 | 1 | Chemie (MRD) PubChem (7870) PubChem (5288834) PubChem (5288845) | |||
| 9 | L, M, N (A, B, C) | water | water | 18.0 | 351 | Chemie (HOH) |
Sequence modifications
A, B, C: 183 - 363 (UniProt: A0MK70)
| PDB | External Database | Details |
|---|---|---|
| Met 155 | - | initiating methionine |
| Arg 156 | - | expression tag |
| Gly 157 | - | expression tag |
| Ser 158 | - | expression tag |
| His 159 | - | expression tag |
| His 160 | - | expression tag |
| His 161 | - | expression tag |
| His 162 | - | expression tag |
| His 163 | - | expression tag |
| His 164 | - | expression tag |
| Gly 165 | - | expression tag |
| Ser 166 | - | expression tag |
| Gly 167 | - | expression tag |
| Ser 168 | - | expression tag |
| Gly 169 | - | expression tag |
| Ser 170 | - | expression tag |
| Gly 171 | - | expression tag |
| Ile 172 | - | expression tag |
| Glu 173 | - | expression tag |
| Gly 174 | - | expression tag |
| Arg 175 | - | expression tag |
| Pro 176 | - | expression tag |
| Tyr 177 | - | expression tag |
| Asn 178 | - | expression tag |
| Gly 179 | - | expression tag |
| Thr 180 | - | expression tag |
| Gly 181 | - | expression tag |
| Ser 182 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 67262.6 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 1374.5 | |
| All* | Total formula weight | 68637.1 |
