4XL3

Crystal structure of reduced form of thiolase from Clostridium acetobutylicum

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Acetyl-CoA acetyltransferase	polymer	400	42345.5	2	UniProt (F0K5D8) Pfam (PF00108) Pfam (PF02803) UniProt (by SIFTS) (A0A0R4I970) In PDB	Clostridium acetobutylicum (strain EA 2018)
2	A, B	GLYCEROL	non-polymer		92.1	6	Chemie (GOL)
3		water	water		18.0	786	Chemie (HOH)

Sequence modifications

A, B: 1 - 392 (UniProt: F0K5D8)

PDB	External Database	Details
Ser 378	Cys 378	engineered mutation
Leu 393	-	expression tag
Glu 394	-	expression tag
His 395	-	expression tag
His 396	-	expression tag
His 397	-	expression tag
His 398	-	expression tag
His 399	-	expression tag
His 400	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	84691.0
Non-Polymers*	Number of molecules	6
	Total formula weight	552.6
All*	Total formula weight	85243.6

*Water molecules are not included.