4XJQ

The catalytic mechanism of human parainfluenza virus type 3 haemagglutinin-neuraminidase revealed

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Hemagglutinin-neuraminidase	polymer	454	50903.6	2	UniProt (G8G134) Pfam (PF00423)	Human parainfluenza virus 3
2	C (C)	alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		748.7	1	In PDB GlyTouCan (G81315DD)
3	D (D)	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		424.4	1	In PDB GlyTouCan (G42666HT)
4	E, M (A, B)	CALCIUM ION	non-polymer		40.1	2	Chemie (CA)
5	F, O (A, B)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	2	Chemie (NAG)
6	G, H, I, J, P... (A, B)	1,2-ETHANEDIOL	non-polymer		62.1	8	Chemie (EDO)
7	K, L (A)	GLYCEROL	non-polymer		92.1	2	Chemie (GOL)
8	N, Q (B)	SULFATE ION	non-polymer		96.1	2	Chemie (SO4)
9	U, V (A, B)	water	water		18.0	638	Chemie (HOH)

Sequence modifications

A, B: 125 - 572 (UniProt: G8G134)

PDB	External Database	Details
His 573	-	expression tag
His 574	-	expression tag
His 575	-	expression tag
His 576	-	expression tag
His 577	-	expression tag
His 578	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	101807.3
Branched	Number of molecules	2
	Total formula weight	1173.1
Non-Polymers*	Number of molecules	16
	Total formula weight	1395.4
All*	Total formula weight	104375.8

*Water molecules are not included.