4XHB
Crystal structure of the NanB sialidase from streptococcus pneumoniae in complex with pentanediol and CHES
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Sialidase B | polymer | 658 | 73519.9 | 1 | UniProt (Q54727) Pfam (PF02973) Pfam (PF02012) Pfam (PF13088) | Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4) | Neuraminidase B |
| 2 | B (A) | (1R,2S)-cyclopentane-1,2-diol | non-polymer | 102.1 | 1 | Chemie (17Y) | |||
| 3 | C (A) | 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID | non-polymer | 207.3 | 1 | Chemie (NHE) | |||
| 4 | D (A) | water | water | 18.0 | 675 | Chemie (HOH) |
Sequence modifications
A: 39 - 696 (UniProt: Q54727)
| PDB | External Database | Details |
|---|---|---|
| Gly 643 | Asp 643 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 73519.9 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 309.4 | |
| All* | Total formula weight | 73829.3 |
