4XH6
Crystal structure of proto-oncogene kinase Pim1 bound to hispidulin
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Serine/threonine-protein kinase pim-1 | polymer | 294 | 33963.5 | 1 | UniProt (P11309) Pfam (PF00069) In PDB | Homo sapiens (Human) | Proto-oncogene serine/threonine-protein kinase Pim-1 |
2 | A | 5,7-dihydroxy-2-(4-hydroxyphenyl)-6-methoxy-4H-chromen-4-one | non-polymer | 300.3 | 1 | Chemie (HUL) | |||
3 | water | water | 18.0 | 65 | Chemie (HOH) |
Sequence modifications
A: 29 - 313 (UniProt: P11309)
PDB | External Database | Details |
---|---|---|
Met 28 | - | expression tag |
Val 314 | - | expression tag |
Asp 315 | - | expression tag |
His 316 | - | expression tag |
His 317 | - | expression tag |
His 318 | - | expression tag |
His 319 | - | expression tag |
His 320 | - | expression tag |
His 321 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 33963.5 | |
Non-Polymers* | Number of molecules | 1 |
Total formula weight | 300.3 | |
All* | Total formula weight | 34263.8 |