4XGC

Crystal structure of the eukaryotic origin recognition complex

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	B	Origin recognition complex subunit 2	polymer	354	40106.8	1	UniProt (Q24168) Pfam (PF04084) In PDB	Drosophila melanogaster (Fruit fly)	DmORC2
2	C	Origin recognition complex subunit 3	polymer	676	77650.1	1	UniProt (Q7K2L1) Pfam (PF07034) Pfam (PF19675) Pfam (PF18137) In PDB	Drosophila melanogaster (Fruit fly)	FI24229p1,GH28787p,LP02234p1,Latheo
3	E	Origin recognition complex subunit 5	polymer	460	52175.1	1	UniProt (Q24169) Pfam (PF13191) Pfam (PF21639) Pfam (PF14630) In PDB	Drosophila melanogaster (Fruit fly)
4	A	Origin recognition complex subunit 1	polymer	393	43910.8	1	UniProt (O16810) Pfam (PF00004) Pfam (PF17872) Pfam (PF09079) In PDB	Drosophila melanogaster (Fruit fly)	DmORC1
5	G	Origin recognition complex subunit 2	polymer	41	3507.3	1		Drosophila melanogaster (Fruit fly)
6	F	Origin recognition complex subunit 6	polymer	72	8204.3	1	UniProt (Q9Y1B2) In PDB	Drosophila melanogaster (Fruit fly)
7	D	Origin recognition complex subunit 4	polymer	459	52004.9	1	UniProt (Q9W102) Pfam (PF00004) Pfam (PF14629) In PDB	Drosophila melanogaster (Fruit fly)	LD43280p
8	B	POTASSIUM ION	non-polymer		39.1	1	Chemie (K)
9	E	CHLORIDE ION	non-polymer		35.5	1	Chemie (CL)

Sequence modifications

B: 266 - 618 (UniProt: Q24168)

PDB	External Database	Details
Met 265	-	initiating methionine

C: 47 - 721 (UniProt: Q7K2L1)

PDB	External Database	Details
Met 46	-	initiating methionine

A: 533 - 924 (UniProt: O16810)

PDB	External Database	Details
Met 532	-	initiating methionine

F: 187 - 257 (UniProt: Q9Y1B2)

PDB	External Database	Details
Met 186	-	initiating methionine

Contents of the asymmetric unit

Polymers	Number of chains	7
	Total formula weight	277559.2
Non-Polymers*	Number of molecules	2
	Total formula weight	74.6
All*	Total formula weight	277633.8

*Water molecules are not included.