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4XEK

Pyk2-FAT domain in complex with leupaxin LD4 motif

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Protein-tyrosine kinase 2-betapolymer13915228.51UniProt (Q14289)
Pfam (PF03623)
Homo sapiens (Human)Calcium-dependent tyrosine kinase,CADTK,Calcium-regulated non-receptor proline-rich tyrosine kinase,Cell adhesion kinase beta,CAKB,Focal adhesion kinase 2,FADK 2,Proline-rich tyrosine kinase 2,Related adhesion focal tyrosine kinase,RAFTK
2B
(C)
19-mer peptide containing Leupaxin LD4 motifpolymer192090.41UniProt (by SIFTS) (O60711)Homo sapiens
3C, D
(A, C)
waterwater18.067Chemie (HOH)
Sequence modifications
A: 871 - 1005 (UniProt: Q14289)
PDBExternal DatabaseDetails
Gly 867-expression tag
Ser 868-expression tag
His 869-expression tag
Met 870-expression tag
Ser 899Cys 899engineered mutation
Ala 972Cys 972engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight17318.9
All*Total formula weight17318.9
*Water molecules are not included.

239803

PDB entries from 2025-08-06

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