4XE4
Coagulation Factor XII protease domain crystal structure
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Coagulation factor XII | polymer | 255 | 27633.0 | 1 | UniProt (P00748) Pfam (PF00089) | Homo sapiens (Human) | Hageman factor,HAF |
| 2 | B (B) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 627.6 | 1 | In PDB BIRD (PRD_900017) GlyTouCan (G47362BJ) | triacetyl-beta-chitotriose | ||
| 3 | C (A) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 4 | D (A) | water | water | 18.0 | 78 | Chemie (HOH) |
Sequence modifications
A: 354 - 596 (UniProt: P00748)
| PDB | External Database | Details |
|---|---|---|
| Ser 467 | Cys 486 | engineered mutation |
| His 597 | - | expression tag |
| His 598 | - | expression tag |
| Thr 599 | - | expression tag |
| Gly 600 | - | expression tag |
| Thr 601 | - | expression tag |
| Arg 602 | - | expression tag |
| His 603 | - | expression tag |
| His 604 | - | expression tag |
| His 605 | - | expression tag |
| His 606 | - | expression tag |
| His 607 | - | expression tag |
| His 608 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 27633.0 | |
| Branched | Number of molecules | 1 |
| Total formula weight | 627.6 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 92.1 | |
| All* | Total formula weight | 28352.6 |
