4XBL

Crystal Structure of Human Galectin-1 in Complex with Type 1 N-acetyllactosamine

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Galectin-1	polymer	154	17031.2	2	UniProt (P09382) Pfam (PF00337)	Homo sapiens (Human)	Gal-1,14 kDa laminin-binding protein,HLBP14,14 kDa lectin,Beta-galactoside-binding lectin L-14-I,Galaptin,HBL,HPL,Lactose-binding lectin 1,Lectin galactoside-binding soluble 1,Putative MAPK-activating protein PM12,S-Lac lectin 1
2	C, D (C, D)	beta-D-galactopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		383.3	2	In PDB GlyTouCan (G00056MO)
3	E, F (A, B)	water	water		18.0	105	Chemie (HOH)

Sequence modifications

A, B: 0 - 134 (UniProt: P09382)

PDB	External Database	Details
Gly -19	-	expression tag
Ser -18	-	expression tag
Ser -17	-	expression tag
His -16	-	expression tag
His -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
His -11	-	expression tag
Ser -10	-	expression tag
Ser -9	-	expression tag
Gly -8	-	expression tag
Leu -7	-	expression tag
Val -6	-	expression tag
Pro -5	-	expression tag
Arg -4	-	expression tag
Gly -3	-	expression tag
Ser -2	-	expression tag
His -1	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	34062.4
Branched	Number of molecules	2
	Total formula weight	766.7
All*	Total formula weight	34829.1

*Water molecules are not included.