4X9R
PLK-1 polo-box domain in complex with Bioactive Imidazolium-containing phosphopeptide macrocycle 3B
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A (A) | Serine/threonine-protein kinase PLK1 | polymer | 237 | 27285.2 | 1 | UniProt (P53350) Pfam (PF00659) | Homo sapiens (Human) | Polo-like kinase 1,PLK-1,Serine/threonine-protein kinase 13,STPK13 |
2 | B (B) | Phosphopeptide macrocycle 3B | polymer | 6 | 962.1 | 1 | synthetic construct | 1-(1-methylethyl)-1H-benzimidazole-2-sulfonic acid | |
3 | C, D (A, B) | water | water | 18.0 | 189 | Chemie (HOH) |
Sequence modifications
A: 371 - 603 (UniProt: P53350)
PDB | External Database | Details |
---|---|---|
Gly 367 | - | expression tag |
Ala 368 | - | expression tag |
His 369 | - | expression tag |
Met 370 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 28247.3 | |
All* | Total formula weight | 28247.3 |