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4X9R

PLK-1 polo-box domain in complex with Bioactive Imidazolium-containing phosphopeptide macrocycle 3B

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Serine/threonine-protein kinase PLK1polymer23727285.21UniProt (P53350)
Pfam (PF00659)
Homo sapiens (Human)Polo-like kinase 1,PLK-1,Serine/threonine-protein kinase 13,STPK13
2B
(B)
Phosphopeptide macrocycle 3Bpolymer6962.11synthetic construct1-(1-methylethyl)-1H-benzimidazole-2-sulfonic acid
3C, D
(A, B)
waterwater18.0189Chemie (HOH)
Sequence modifications
A: 371 - 603 (UniProt: P53350)
PDBExternal DatabaseDetails
Gly 367-expression tag
Ala 368-expression tag
His 369-expression tag
Met 370-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight28247.3
All*Total formula weight28247.3
*Water molecules are not included.

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PDB entries from 2024-10-30

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