4X91
Crystal structure of Lysosomal Phospholipase A2 in complex with Isopropyl dodec-11-enylfluorophosphonate (IDFP)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Group XV phospholipase A2 | polymer | 380 | 43121.0 | 4 | UniProt (Q8NCC3) Pfam (PF02450) | Homo sapiens (Human) | 1-O-acylceramide synthase,ACS,LCAT-like lysophospholipase,LLPL,Lysophospholipase 3,Lysosomal phospholipase A2,LPLA2 |
| 2 | AA, BA, CA, DA, E... (C, A, D, B) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 16 | Chemie (NAG) | |||
| 3 | EA, I, OA, U (C, A, D, B) | propan-2-yl (R)-dodec-11-en-1-ylphosphonofluoridate | non-polymer | 292.4 | 4 | Chemie (TO4) | |||
| 4 | FA, J, PA, V (C, A, D, B) | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID | non-polymer | 238.3 | 4 | Chemie (EPE) | |||
| 5 | GA, HA, K, L, M... (C, A, D, B) | PHOSPHATE ION | non-polymer | 95.0 | 10 | Chemie (PO4) | |||
| 6 | IA, JA, O, P, SA... (C, A, D, B) | (4S)-2-METHYL-2,4-PENTANEDIOL | non-polymer | 118.2 | 7 | Chemie (MPD) | |||
| 7 | TA, UA, VA, WA (A, B, C, D) | water | water | 18.0 | 513 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 1 - 379 (UniProt: Q8NCC3)
| PDB | External Database | Details |
|---|---|---|
| Gly 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 172484.1 | |
| Non-Polymers* | Number of molecules | 41 |
| Total formula weight | 7439.0 | |
| All* | Total formula weight | 179923.1 |
