4X6I
Development of N-(Functionalized benzoyl)-homocycloleucyl-glycinonitriles as Potent Cathepsin K Inhibitors.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Cathepsin K | polymer | 215 | 23523.5 | 1 | UniProt (P43235) Pfam (PF00112) In PDB | Homo sapiens (Human) | Cathepsin O,Cathepsin O2,Cathepsin X |
| 2 | A | 2-amino-4-bromo-N-{1-[(cyanomethyl)carbamoyl]cyclohexyl}benzamide | non-polymer | 379.3 | 1 | Chemie (3Y1) | |||
| 3 | A | SULFATE ION | non-polymer | 96.1 | 5 | Chemie (SO4) | |||
| 4 | water | water | 18.0 | 201 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 23523.5 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 859.6 | |
| All* | Total formula weight | 24383.0 |
