4X55

Structure of the class D Beta-Lactamase OXA-225 K82D in Acyl-Enzyme Complex with Ceftazidime

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Beta-lactamase OXA-225	polymer	253	28761.1	2	UniProt (G5DE28) Pfam (PF00905)	Acinetobacter baumannii	OXA-23 class D beta-lactamase
2	C, D (A, B)	1-({(2R)-2-[(1R)-1-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-{[(2-carboxypropan-2-yl)oxy]imino}acetyl]amino}-2-oxoethyl]-4-carboxy-3,6-dihydro-2H-1,3-thiazin-5-yl}methyl)pyridinium	non-polymer		549.6	2	Chemie (CTJ)
3	E, F (A, B)	water	water		18.0	192	Chemie (HOH)

Sequence modifications

A, B: 22 - 273 (UniProt: G5DE28)

PDB	External Database	Details
Met 21	-	initiating methionine
Asp 82	Lys 82	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	57522.1
Non-Polymers*	Number of molecules	2
	Total formula weight	1099.2
All*	Total formula weight	58621.3

*Water molecules are not included.