4X55
Structure of the class D Beta-Lactamase OXA-225 K82D in Acyl-Enzyme Complex with Ceftazidime
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Beta-lactamase OXA-225 | polymer | 253 | 28761.1 | 2 | UniProt (G5DE28) Pfam (PF00905) In PDB | Acinetobacter baumannii | OXA-23 class D beta-lactamase |
2 | A, B | 1-({(2R)-2-[(1R)-1-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-{[(2-carboxypropan-2-yl)oxy]imino}acetyl]amino}-2-oxoethyl]-4-carboxy-3,6-dihydro-2H-1,3-thiazin-5-yl}methyl)pyridinium | non-polymer | 549.6 | 2 | Chemie (CTJ) | |||
3 | water | water | 18.0 | 192 | Chemie (HOH) |
Sequence modifications
A, B: 22 - 273 (UniProt: G5DE28)
PDB | External Database | Details |
---|---|---|
Met 21 | - | initiating methionine |
Asp 82 | Lys 82 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 57522.1 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 1099.2 | |
All* | Total formula weight | 58621.3 |