4X4A
Crystal structure of the intramolecular trans-sialidase from Ruminococcus gnavus in complex with 2,7-Anhydro-Neu5Ac
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Anhydrosialidase | polymer | 489 | 53992.6 | 1 | UniProt (V8BWT1) | Ruminococcus gnavus ATCC 29149 | |
| 2 | B (A) | 2-ACETYLAMINO-7-(1,2-DIHYDROXY-ETHYL)-3-HYDROXY-6,8-DIOXA-BICYCLO[3.2.1]OCTANE-5-CARBOXYLIC ACID | non-polymer | 291.3 | 1 | Chemie (SKD) | |||
| 3 | C, D, E (A) | GLYCEROL | non-polymer | 92.1 | 3 | Chemie (GOL) | |||
| 4 | F (A) | PHOSPHATE ION | non-polymer | 95.0 | 1 | Chemie (PO4) | |||
| 5 | G (A) | ACETYL GROUP | non-polymer | 44.1 | 1 | Chemie (ACE) | |||
| 6 | H (A) | water | water | 18.0 | 529 | Chemie (HOH) |
Sequence modifications
A: 243 - 723 (UniProt: V8BWT1)
| PDB | External Database | Details |
|---|---|---|
| Gly 235 | - | expression tag |
| Ala 236 | - | expression tag |
| Met 237 | - | expression tag |
| Ala 238 | - | expression tag |
| Asp 239 | - | expression tag |
| Ile 240 | - | expression tag |
| Gly 241 | - | expression tag |
| Ser 242 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 53992.6 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 706.6 | |
| All* | Total formula weight | 54699.2 |
