4X2B
K20A RNA dependent RNA polymerase mutant from Foot-and-Mouth disease Virus complexed with an RNA
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | RNA dependent RNA polymerase | polymer | 481 | 54052.2 | 1 | UniProt (P03311) Pfam (PF00680) | Foot-and-mouth disease virus (FMDV) | |
| 2 | B (B) | RNA template | polymer | 7 | 2236.4 | 1 | synthetic construct | ||
| 3 | C (C) | RNA primer | polymer | 6 | 1906.2 | 1 | synthetic construct | ||
| 4 | D (A) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 5 | E, F (A, B) | water | water | 18.0 | 14 | Chemie (HOH) |
Sequence modifications
A: 1 - 470 (UniProt: P03311)
| PDB | External Database | Details |
|---|---|---|
| Ala 20 | Lys 1877 | engineered mutation |
| Ala 471 | - | expression tag |
| Ala 472 | - | expression tag |
| Ala 473 | - | expression tag |
| Leu 474 | - | expression tag |
| Glu 475 | - | expression tag |
| His 476 | - | expression tag |
| His 477 | - | expression tag |
| His 478 | - | expression tag |
| His 479 | - | expression tag |
| His 480 | - | expression tag |
| His 481 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 58194.8 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 24.3 | |
| All* | Total formula weight | 58219.1 |
