4X1L

Structural basis for mutation-induced destabilization of Profilin 1 in ALS

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Profilin-1	polymer	140	15071.2	1	UniProt (P07737) Pfam (PF00235) In PDB	Homo sapiens (Human)	Epididymis tissue protein Li 184a,Profilin I
2	A	PHOSPHATE ION	non-polymer		95.0	1	Chemie (PO4)
3		water	water		18.0	64	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	15071.2
Non-Polymers*	Number of molecules	1
	Total formula weight	95.0
All*	Total formula weight	15166.2

*Water molecules are not included.