4X0T
Structure ALDH7A1 inactivated by 4-diethylaminobenzaldehyde and complexed with NAD+
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Alpha-aminoadipic semialdehyde dehydrogenase | polymer | 513 | 55620.4 | 4 | UniProt (P49419) Pfam (PF00171) | Homo sapiens (Human) | Alpha-AASA dehydrogenase,Aldehyde dehydrogenase family 7 member A1,Antiquitin-1,Betaine aldehyde dehydrogenase,Delta1-piperideine-6-carboxylate dehydrogenase,P6c dehydrogenase |
| 2 | E, G, I, K (A, B, C, D) | NICOTINAMIDE-ADENINE-DINUCLEOTIDE | non-polymer | 663.4 | 4 | Chemie (NAD) | |||
| 3 | F, H, J, L (A, B, C, D) | 4-(diethylamino)benzaldehyde | non-polymer | 177.2 | 4 | Chemie (3W9) | |||
| 4 | M, N, O, P (A, B, C, D) | water | water | 18.0 | 314 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 1 - 511 (UniProt: P49419)
| PDB | External Database | Details |
|---|---|---|
| Gly -1 | - | expression tag |
| His 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 222481.5 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 3362.7 | |
| All* | Total formula weight | 225844.1 |
