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4X0Q

Ternary complex of human DNA polymerase theta C-terminal domain binding ddGTP opposite dCMP

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
DNA polymerase thetapolymer77286735.52UniProt (O75417)
Pfam (PF00476)
Homo sapiens (Human)DNA polymerase eta
2C, E
(E, G)
DNA (5'-D(*CP*GP*TP*CP*CP*AP*AP*TP*GP*AP*CP*AP*G)-3')polymer175157.42synthetic construct
3D, F
(F, H)
DNA (5'-D(P*CP*TP*GP*TP*CP*AP*TP*TP*G)-3')polymer133998.62synthetic construct
4G, H, K, L
(A, B)
GLYCEROLnon-polymer92.14Chemie (GOL)
5I, M
(A, B)
MAGNESIUM IONnon-polymer24.32Chemie (MG)
6J, N
(A, B)
2'-3'-DIDEOXYGUANOSINE-5'-TRIPHOSPHATEnon-polymer491.22Chemie (DG3)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains6
Total formula weight191782.8
Non-Polymers*Number of molecules8
Total formula weight1399.3
All*Total formula weight193182.2
*Water molecules are not included.

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PDB entries from 2025-06-11

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