4WYW

Mutant K20E of 3D polymerase from Foot-and-Mouth Disease Virus

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	RNA-directed RNA polymerase 3D-POL	polymer	481	54110.3	1	UniProt (P03311)	Foot-and-mouth disease virus (FMDV)
2	B (A)	TRIPHOSPHATE	non-polymer		258.0	1	Chemie (3PO)
3	C, D, E, F (A)	GLYCEROL	non-polymer		92.1	4	Chemie (GOL)
4	G (A)	ACETATE ION	non-polymer		59.0	1	Chemie (ACT)
5	H (A)	water	water		18.0	281	Chemie (HOH)

Sequence modifications

A: 1 - 470 (UniProt: P03311)

PDB	External Database	Details
Glu 20	Lys 1849	engineered mutation
Ala 471	-	expression tag
Ala 472	-	expression tag
Ala 473	-	expression tag
Leu 474	-	expression tag
Glu 475	-	expression tag
His 476	-	expression tag
His 477	-	expression tag
His 478	-	expression tag
His 479	-	expression tag
His 480	-	expression tag
His 481	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	54110.3
Non-Polymers*	Number of molecules	6
	Total formula weight	685.4
All*	Total formula weight	54795.6

*Water molecules are not included.