4WX6

Crystal structure of human adenovirus 8 protease with an irreversible vinyl sulfone inhibitor

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C (A, C)	Protease	polymer	204	22993.3	2	UniProt (B9A5C1)	Human adenovirus D serotype 8 (HAdV-8)
2	B, D (B, D)	PVI	polymer	11	1370.7	2	UniProt (B9A5F5)	Human adenovirus D serotype 8
3	E, F (A, C)	N-[(2S)-2-(3,5-dichlorophenyl)-2-(ethylamino)acetyl]-3-methyl-L-valyl-N-[3-(methylsulfonyl)propyl]glycinamide	non-polymer		537.5	2	Chemie (3VK)
4	G, H, I, J (A, B, C, D)	water	water		18.0	28	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	48728.0
Non-Polymers*	Number of molecules	2
	Total formula weight	1075.0
All*	Total formula weight	49803.0

*Water molecules are not included.