4WWI

Crystal structure of the C domain of staphylococcal protein A in complex with the Fc fragment of human IgG at 2.3 Angstrom resolution

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C (A, B, C)	Immunoglobulin G-binding protein A	polymer	58	6637.4	3	UniProt (P38507) Pfam (PF02216)	Staphylococcus aureus	IgG-binding protein A,Staphylococcal protein A
2	D, E, F (D, E, F)	Ig gamma-3 chain C region	polymer	220	25124.4	3	UniProt (P01860) Pfam (PF07654)	Homo sapiens (Human)	HDC,Heavy chain disease protein
3	G, H, I, J, K... (A, B, C, D, E...)	water	water		18.0	165	Chemie (HOH)

Sequence modifications

D, E, F: 238 - 447 (UniProt: P01860)

PDB	External Database	Details
Phe 296	Tyr 226	conflict
His 435	Arg 365	conflict
Tyr 436	Phe 366	conflict
Gly 448	-	expression tag
Ser 449	-	expression tag
Leu 450	-	expression tag
Glu 451	-	expression tag
His 452	-	expression tag
His 453	-	expression tag
His 454	-	expression tag
His 455	-	expression tag
His 456	-	expression tag
His 457	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	95285.1
All*	Total formula weight	95285.1

*Water molecules are not included.