4WVO
An engineered PYR1 mandipropamid receptor in complex with mandipropamid and HAB1
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Abscisic acid receptor PYR1 | polymer | 181 | 20659.3 | 1 | UniProt (O49686) Pfam (PF03364) | Arabidopsis thaliana (Mouse-ear cress) | ABI1-binding protein 6,Protein PYRABACTIN RESISTANCE 1,Regulatory components of ABA receptor 11 |
| 2 | B (B) | Protein phosphatase 2C 16 | polymer | 331 | 36582.9 | 1 | UniProt (Q9CAJ0) Pfam (PF00481) | Arabidopsis thaliana (Mouse-ear cress) | AtPP2C16,AtP2C-HA,Protein HYPERSENSITIVE TO ABA 1,Protein phosphatase 2C HAB1,PP2C HAB1 |
| 3 | C (A) | (2S)-2-(4-chlorophenyl)-N-{2-[3-methoxy-4-(prop-2-yn-1-yloxy)phenyl]ethyl}-2-(prop-2-yn-1-yloxy)ethanamide | non-polymer | 411.9 | 1 | Chemie (3UZ) | |||
| 4 | D, E, F (B) | MAGNESIUM ION | non-polymer | 24.3 | 3 | Chemie (MG) | |||
| 5 | G, H (A, B) | water | water | 18.0 | 192 | Chemie (HOH) |
Sequence modifications
A: 1 - 181 (UniProt: O49686)
B: 178 - 505 (UniProt: Q9CAJ0)
| PDB | External Database | Details |
|---|---|---|
| Arg 59 | Lys 59 | engineered mutation |
| Ile 81 | Val 81 | engineered mutation |
| Ala 108 | Phe 108 | engineered mutation |
| Leu 159 | Phe 159 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Gly 175 | - | expression tag |
| Ala 176 | - | expression tag |
| Met 177 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 57242.2 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 484.8 | |
| All* | Total formula weight | 57727.0 |
