4WUU
Structure of ESK1 in complex with HLA-A*0201/WT1
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | HLA class I histocompatibility antigen, A-2 alpha chain | polymer | 296 | 34081.6 | 1 | UniProt (P01892) Pfam (PF00129) Pfam (PF07654) UniProt (by SIFTS) (P04439) | Homo sapiens (Human) | MHC class I antigen A*2 |
| 2 | B (B) | Beta-2-microglobulin | polymer | 100 | 11879.4 | 1 | UniProt (P61769) Pfam (PF07654) | Homo sapiens (Human) | |
| 3 | C (C) | ARG-MET-PHE-PRO-ASN-ALA-PRO-TYR-LEU | polymer | 9 | 1109.3 | 1 | UniProt (by SIFTS) (P19544) | Homo sapiens | |
| 4 | D (D) | ESK1 | polymer | 216 | 22750.0 | 1 | Homo sapiens (Human) | ||
| 5 | E (E) | IMMUNOGLOBULIN HEAVY CHAIN | polymer | 223 | 24121.9 | 1 | Homo sapiens (Human) |
Sequence modifications
A: 1 - 276 (UniProt: P01892)
B: 1 - 99 (UniProt: P61769)
| PDB | External Database | Details |
|---|---|---|
| Met 0 | - | initiating methionine |
| Gly 277 | - | expression tag |
| Ser 278 | - | expression tag |
| Gly 279 | - | expression tag |
| Gly 280 | - | expression tag |
| Gly 281 | - | expression tag |
| Leu 282 | - | expression tag |
| Asn 283 | - | expression tag |
| Asp 284 | - | expression tag |
| Ile 285 | - | expression tag |
| Phe 286 | - | expression tag |
| Glu 287 | - | expression tag |
| Ala 288 | - | expression tag |
| Gln 289 | - | expression tag |
| Lys 290 | - | expression tag |
| Ile 291 | - | expression tag |
| Gly 292 | - | expression tag |
| Trp 293 | - | expression tag |
| His 294 | - | expression tag |
| Glu 295 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Met 0 | - | initiating methionine |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 5 |
| Total formula weight | 93942.2 | |
| All* | Total formula weight | 93942.2 |
