4WU2
Structure of the PTP-like myo-inositol phosphatase from Selenomonas ruminantium in complex with myo-inositol-(1,4,5)-trikisphosphate
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Myo-inositol phosphohydrolase | polymer | 342 | 39130.0 | 2 | UniProt (Q7WUJ1) Pfam (PF14566) | Selenomonas ruminantium | |
| 2 | C, G (A, B) | D-MYO-INOSITOL-1,4,5-TRIPHOSPHATE | non-polymer | 420.1 | 2 | Chemie (I3P) | |||
| 3 | D, H (A, B) | PHOSPHATE ION | non-polymer | 95.0 | 2 | Chemie (PO4) | |||
| 4 | E, F, J, K (A, B) | GLYCEROL | non-polymer | 92.1 | 4 | Chemie (GOL) | |||
| 5 | I (B) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 6 | L, M (A, B) | water | water | 18.0 | 484 | Chemie (HOH) |
Sequence modifications
A, B: 28 - 346 (UniProt: Q7WUJ1)
| PDB | External Database | Details |
|---|---|---|
| Met 5 | - | initiating methionine |
| Gly 6 | - | expression tag |
| Ser 7 | - | expression tag |
| Ser 8 | - | expression tag |
| His 9 | - | expression tag |
| His 10 | - | expression tag |
| His 11 | - | expression tag |
| His 12 | - | expression tag |
| His 13 | - | expression tag |
| His 14 | - | expression tag |
| Ser 15 | - | expression tag |
| Ser 16 | - | expression tag |
| Gly 17 | - | expression tag |
| Leu 18 | - | expression tag |
| Val 19 | - | expression tag |
| Pro 20 | - | expression tag |
| Arg 21 | - | expression tag |
| Gly 22 | - | expression tag |
| Ser 23 | - | expression tag |
| His 24 | - | expression tag |
| Met 25 | - | expression tag |
| Ala 26 | - | expression tag |
| Ser 27 | - | expression tag |
| Ser 252 | Cys 252 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 78260.0 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 1434.0 | |
| All* | Total formula weight | 79694.0 |
