4WU2

Structure of the PTP-like myo-inositol phosphatase from Selenomonas ruminantium in complex with myo-inositol-(1,4,5)-trikisphosphate

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Myo-inositol phosphohydrolase	polymer	342	39130.0	2	UniProt (Q7WUJ1) Pfam (PF14566) In PDB	Selenomonas ruminantium
2	A, B	D-MYO-INOSITOL-1,4,5-TRIPHOSPHATE	non-polymer		420.1	2	Chemie (I3P)
3	A, B	PHOSPHATE ION	non-polymer		95.0	2	Chemie (PO4)
4	A, B	GLYCEROL	non-polymer		92.1	4	Chemie (GOL)
5	B	CHLORIDE ION	non-polymer		35.5	1	Chemie (CL)
6		water	water		18.0	484	Chemie (HOH)

Sequence modifications

A, B: 28 - 346 (UniProt: Q7WUJ1)

PDB	External Database	Details
Met 5	-	initiating methionine
Gly 6	-	expression tag
Ser 7	-	expression tag
Ser 8	-	expression tag
His 9	-	expression tag
His 10	-	expression tag
His 11	-	expression tag
His 12	-	expression tag
His 13	-	expression tag
His 14	-	expression tag
Ser 15	-	expression tag
Ser 16	-	expression tag
Gly 17	-	expression tag
Leu 18	-	expression tag
Val 19	-	expression tag
Pro 20	-	expression tag
Arg 21	-	expression tag
Gly 22	-	expression tag
Ser 23	-	expression tag
His 24	-	expression tag
Met 25	-	expression tag
Ala 26	-	expression tag
Ser 27	-	expression tag
Ser 252	Cys 252	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	78260.0
Non-Polymers*	Number of molecules	9
	Total formula weight	1434.0
All*	Total formula weight	79694.0

*Water molecules are not included.