4WS7
Crystal structure of Mycobacterium tuberculosis uracil-DNA glycosylase in complex with 5-chlorouracil, Form II
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Uracil-DNA glycosylase | polymer | 238 | 25813.5 | 1 | UniProt (P9WFQ9) Pfam (PF03167) | Mycobacterium tuberculosis | UDG |
| 2 | B (A) | 5-chloropyrimidine-2,4(1H,3H)-dione | non-polymer | 146.5 | 1 | Chemie (5UC) | |||
| 3 | C (A) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 4 | D (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 1 | Chemie (EDO) | |||
| 5 | E (A) | water | water | 18.0 | 238 | Chemie (HOH) |
Sequence modifications
A: 1 - 227 (UniProt: P9WFQ9)
| PDB | External Database | Details |
|---|---|---|
| Met -10 | - | initiating methionine |
| His -9 | - | expression tag |
| His -8 | - | expression tag |
| His -7 | - | expression tag |
| His -6 | - | expression tag |
| His -5 | - | expression tag |
| His -4 | - | expression tag |
| Gly -3 | - | expression tag |
| Met -2 | - | expression tag |
| Ala -1 | - | expression tag |
| Ser 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 25813.5 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 244.1 | |
| All* | Total formula weight | 26057.6 |
