4WOE
The duplicated taurocyamine kinase from Schistosoma mansoni with bound transition state analog (TSA) components
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Taurocyamine kinase | polymer | 716 | 80422.7 | 2 | UniProt (P16641) Pfam (PF02807) Pfam (PF00217) | Schistosoma mansoni (Blood fluke) | ATP:guanidino kinase Smc74,ATP:guanidino phosphotransferase,SmGK |
| 2 | C, D, K, L (A, B) | ADENOSINE-5'-DIPHOSPHATE | non-polymer | 427.2 | 4 | Chemie (ADP) | |||
| 3 | E, F, M, N (A, B) | Taurocyamine | non-polymer | 167.2 | 4 | Chemie (3S5) | |||
| 4 | G, H, O (A, B) | MAGNESIUM ION | non-polymer | 24.3 | 3 | Chemie (MG) | |||
| 5 | I, J (A) | NITRATE ION | non-polymer | 62.0 | 2 | Chemie (NO3) | |||
| 6 | P, Q (A, B) | water | water | 18.0 | 739 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 716 (UniProt: P16641)
| PDB | External Database | Details |
|---|---|---|
| Val 11 | Ala 41 | engineered mutation |
| Gly 235 | Asp 265 | engineered mutation |
| Thr 237 | Ile 267 | engineered mutation |
| Gly 493 | Asp 523 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 160845.4 | |
| Non-Polymers* | Number of molecules | 13 |
| Total formula weight | 2574.5 | |
| All* | Total formula weight | 163419.9 |
