4WOE
The duplicated taurocyamine kinase from Schistosoma mansoni with bound transition state analog (TSA) components
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Taurocyamine kinase | polymer | 716 | 80422.7 | 2 | UniProt (P16641) Pfam (PF02807) Pfam (PF00217) In PDB | Schistosoma mansoni (Blood fluke) | ATP:guanidino kinase Smc74,ATP:guanidino phosphotransferase,SmGK |
2 | A, B | ADENOSINE-5'-DIPHOSPHATE | non-polymer | 427.2 | 4 | Chemie (ADP) | |||
3 | A, B | Taurocyamine | non-polymer | 167.2 | 4 | Chemie (3S5) | |||
4 | A, B | MAGNESIUM ION | non-polymer | 24.3 | 3 | Chemie (MG) | |||
5 | A | NITRATE ION | non-polymer | 62.0 | 2 | Chemie (NO3) | |||
6 | water | water | 18.0 | 739 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 716 (UniProt: P16641)
PDB | External Database | Details |
---|---|---|
Val 11 | Ala 41 | engineered mutation |
Gly 235 | Asp 265 | engineered mutation |
Thr 237 | Ile 267 | engineered mutation |
Gly 493 | Asp 523 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 160845.4 | |
Non-Polymers* | Number of molecules | 13 |
Total formula weight | 2574.5 | |
All* | Total formula weight | 163419.9 |