4WO4

The molecular bases of Delta/Alpha beta T cell-mediated antigen recognition.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Antigen-presenting glycoprotein CD1d	polymer	274	31184.2	1	UniProt (P15813) Pfam (PF16497) Pfam (PF07654)	Homo sapiens (Human)	R3G1
2	B (B)	Beta-2-microglobulin	polymer	100	11879.4	1	UniProt (P61769) Pfam (PF07654)	Homo sapiens (Human)
3	C (C)	TCR variable DELTA 1 CHAIN and TCR constant Alpha	polymer	207	23186.1	1		Homo sapiens
4	D (D)	TCR variable BETA 2 (TRVB20) chain and TCR constant BETA	polymer	245	27339.6	1		Homo sapiens
5	E (E)	beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose	branched		732.7	1	In PDB GlyTouCan (G32152BH)
6	F (F)	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		424.4	1	In PDB GlyTouCan (G42666HT)
7	G (G)	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose	branched		570.5	1	In PDB GlyTouCan (G21290RB)
8	H (A)	(15Z)-N-[(2S,3S,4R)-1-(alpha-D-galactopyranosyloxy)-3,4-dihydroxyoctadecan-2-yl]tetracos-15-enamide	non-polymer		828.3	1	Chemie (JLS)
9	I, J, K, L (A, B, C, D)	water	water		18.0	205	Chemie (HOH)

Sequence modifications

A: 6 - 277 (UniProt: P15813)

PDB	External Database	Details
Pro 278	-	expression tag
Arg 279	-	expression tag

B: 1 - 99 (UniProt: P61769)

PDB	External Database	Details
Met 0	-	initiating methionine

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	93589.2
Branched	Number of molecules	3
	Total formula weight	1727.6
Non-Polymers*	Number of molecules	1
	Total formula weight	828.3
All*	Total formula weight	96145.1

*Water molecules are not included.