4WNI
Crystal structure of the T229K mutant of human GAPDH at 2.3 angstroems resolution
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (O, A, B, C) | Glyceraldehyde-3-phosphate dehydrogenase | polymer | 335 | 36127.2 | 4 | UniProt (P04406) Pfam (PF00044) Pfam (PF02800) | Homo sapiens (Human) | GAPDH,Peptidyl-cysteine S-nitrosylase GAPDH |
| 2 | E, H, I (O, A, B) | NICOTINAMIDE-ADENINE-DINUCLEOTIDE | non-polymer | 663.4 | 3 | Chemie (NAD) | |||
| 3 | F, G, J (O, B) | ZINC ION | non-polymer | 65.4 | 3 | Chemie (ZN) | |||
| 4 | K, L, M, N (O, A, B, C) | water | water | 18.0 | 739 | Chemie (HOH) |
Sequence modifications
O, A, B, C: 1 - 335 (UniProt: P04406)
| PDB | External Database | Details |
|---|---|---|
| Lys 229 | Thr 229 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 144509.0 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 2186.5 | |
| All* | Total formula weight | 146695.5 |
