4WMX
The structure of MBP-MCL1 bound to ligand 6 at 2.0A
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | MBP-MCL1 chimera protein | polymer | 518 | 57310.9 | 1 | UniProt (P0AEX9) UniProt (Q07820) Pfam (PF01547) Pfam (PF00452) In PDB | Escherichia coli | |
| 2 | B | alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose | branched | 342.3 | 1 | In PDB BIRD (PRD_900001) GlyTouCan (G07411ON) | alpha-maltose | ||
| 3 | A | 4-ethenyl-2-[(phenylsulfonyl)amino]benzoic acid | non-polymer | 303.3 | 1 | Chemie (3R7) | |||
| 4 | A | FORMIC ACID | non-polymer | 46.0 | 10 | Chemie (FMT) | |||
| 5 | A | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 6 | water | water | 18.0 | 367 | Chemie (HOH) |
Sequence modifications
A: -195 - 170 (UniProt: P0AEX9)
A: 174 - 321 (UniProt: Q07820)
| PDB | External Database | Details |
|---|---|---|
| Gly -196 | - | expression tag |
| Gly 171 | - | linker |
| Ser 172 | - | linker |
| Glu 173 | - | linker |
| PDB | External Database | Details |
|---|---|---|
| Ala 194 | Lys 194 | engineered mutation |
| Ala 197 | Lys 197 | engineered mutation |
| Ala 201 | Arg 201 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 57310.9 | |
| Branched | Number of molecules | 1 |
| Total formula weight | 342.3 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 787.9 | |
| All* | Total formula weight | 58441.1 |
