4WMV
STRUCTURE OF MBP-MCL1 BOUND TO ligand 4 AT 2.4A
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | MBL-MCL1 chimera protein | polymer | 518 | 57310.9 | 1 | UniProt (P0AEX9) UniProt (Q07820) Pfam (PF01547) Pfam (PF00452) In PDB | Escherichia coli | |
2 | B | alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose | branched | 342.3 | 1 | In PDB BIRD (PRD_900001) GlyTouCan (G07411ON) | alpha-maltose | ||
3 | A | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
4 | A | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
5 | A | 3-chloro-6-fluoro-1-benzothiophene-2-carboxylic acid | non-polymer | 230.6 | 1 | Chemie (3R4) | |||
6 | water | water | 18.0 | 145 | Chemie (HOH) |
Sequence modifications
A: -195 - 170 (UniProt: P0AEX9)
A: 174 - 321 (UniProt: Q07820)
PDB | External Database | Details |
---|---|---|
Gly -196 | - | expression tag |
Gly 171 | - | linker |
Ser 172 | - | linker |
Glu 173 | - | linker |
PDB | External Database | Details |
---|---|---|
Ala 194 | Lys 194 | engineered mutation |
Ala 197 | Lys 197 | engineered mutation |
Ala 201 | Arg 201 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 57310.9 | |
Branched | Number of molecules | 1 |
Total formula weight | 342.3 | |
Non-Polymers* | Number of molecules | 3 |
Total formula weight | 290.4 | |
All* | Total formula weight | 57943.6 |