4WMF
Crystal structure of catalytically inactive MERS-CoV 3CL protease (C148A) in spacegroup P212121
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | MERS-CoV 3CL protease | polymer | 306 | 33322.1 | 3 | UniProt (W6A941) Pfam (PF05409) | Middle East respiratory syndrome coronavirus | |
| 2 | D, E, F, I, J... (A, B, C) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 6 | Chemie (PEG) | |||
| 3 | G, H, K, L, N (B, C) | TETRAETHYLENE GLYCOL | non-polymer | 194.2 | 5 | Chemie (PG4) | |||
| 4 | O, P, Q (A, B, C) | water | water | 18.0 | 758 | Chemie (HOH) |
Sequence modifications
A, B, C: 1 - 306 (UniProt: W6A941)
| PDB | External Database | Details |
|---|---|---|
| Ala 148 | Cys 3395 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 99966.3 | |
| Non-Polymers* | Number of molecules | 11 |
| Total formula weight | 1607.8 | |
| All* | Total formula weight | 101574.2 |
