4WLO

Crystal structure of oxaloacetate and NADH bound MDH2

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	Malate dehydrogenase, mitochondrial	polymer	340	35855.4	4	UniProt (P40926) Pfam (PF00056) Pfam (PF02866)	Homo sapiens (Human)
2	E, G, I, K (A, B, C, D)	1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE	non-polymer		665.4	4	Chemie (NAI) PubChem (928) PubChem (11250888) PubChem (12309341) PubChem (16219774) PubChem (44119956) PubChem (44415182) PubChem (439153) PubChem (124934832) PubChem (126455899) PubChem (134693949) PubChem (12309339) PubChem (12309347) PubChem (140875346) PubChem (162951601) PubChem (162951600) PubChem (164575491) PubChem (169545638) PubChem (170905224) PubChem (174316169) PubChem (94865921) PubChem (94865923) PubChem (124432988) PubChem (124934831) PubChem (124934833) PubChem (129607000) PubChem (129628338) PubChem (146167236) PubChem (162951602) PubChem (174084875)
3	F, H, J, L (A, B, C, D)	OXALOACETATE ION	non-polymer		131.1	4	Chemie (OAA) PubChem (3260017)
4	M, N, O, P (A, B, C, D)	water	water		18.0	25	Chemie (HOH)

Sequence modifications

A, B, C, D: 20 - 338 (UniProt: P40926)

PDB	External Database	Details
Met -1	-	expression tag
Gly 0	-	expression tag
Ser 1	-	expression tag
Ser 2	-	expression tag
His 3	-	expression tag
His 4	-	expression tag
His 5	-	expression tag
His 6	-	expression tag
His 7	-	expression tag
His 8	-	expression tag
Ser 9	-	expression tag
Ser 10	-	expression tag
Gly 11	-	expression tag
Leu 12	-	expression tag
Val 13	-	expression tag
Pro 14	-	expression tag
Arg 15	-	expression tag
Gly 16	-	expression tag
Ser 17	-	expression tag
His 18	-	expression tag
Met 19	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	143421.7
Non-Polymers*	Number of molecules	8
	Total formula weight	3186.0
All*	Total formula weight	146607.7

*Water molecules are not included.