4WKF

Crystal structure of human chitotriosidase-1 catalytic domain in complex with chitobiose (2.5mM) at 1.10 A resolution

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Chitotriosidase-1	polymer	377	42224.3	1	UniProt (Q13231) Pfam (PF00704) In PDB	Homo sapiens (Human)	Chitinase-1
2	B	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		424.4	1	In PDB GlyTouCan (G42666HT)
3		water	water		18.0	362	Chemie (HOH)

Sequence modifications

A: 22 - 387 (UniProt: Q13231)

PDB	External Database	Details
Val 388	-	expression tag
Pro 389	-	expression tag
Arg 390	-	expression tag
Gly 391	-	expression tag
Ser 392	-	expression tag
His 393	-	expression tag
His 394	-	expression tag
His 395	-	expression tag
His 396	-	expression tag
His 397	-	expression tag
His 398	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	42224.3
Branched	Number of molecules	1
	Total formula weight	424.4
All*	Total formula weight	42648.7

*Water molecules are not included.